Verified Buyer
“Years of dandruff and greasy roots. After 2 weeks with Regen the flakes/itch stopped and my hair stopped collapsing by noon. At 8 weeks, both my barber and wife noticed my hairline looks fuller. It’s unscented, drug-free, and gentle enough that I use it most days.”
Regen 2-in-1 Shampoo & Conditioner (Men)
Regen™ Shampoo & Conditioner
Peptide-Powered Scalp Care
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Free shipping
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120 DAY guarantee
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DERM Approved
Verified Buyer
“Years of dandruff and greasy roots. After 2 weeks with Regen the flakes/itch stopped and my hair stopped collapsing by noon. At 8 weeks, both my barber and wife noticed my hairline looks fuller. It’s unscented, drug-free, and gentle enough that I use it most days.”
Regen 2-in-1 Shampoo & Conditioner
❄️ Eliminates Flakes & Itch in 1–2 Weeks
🌱 Resets Scalp Environment for Growth
⚖️ Normalizes Oil & Restores Barrier Balance
🧬 Deposits Peptides That Work Post-Rinse
⚡ Strengthens and Protects Hair Strands
NovaMane™ Regen 2-in-1 is a drug-free formula targeting what actually contributes to hair loss: yeast overgrowth, oil buildup, and scalp inflammation—the same culprits behind both dandruff and follicle dysfunction. Using the PO-BHA-Zn triad dermatologists rely on for scalp control, Regen addresses flaking and itch while GHK Copper peptides continue signaling after rinse, creating a growth-ready scalp environment that amplifies microinfusion results.
Jump to:
From Inflammation to Transformation
See What’s Possible
Healthier Scalp, Fuller Hair
Michael R. Verified Customer
- Reset scalp environment in 2 weeks — flakes & oil under control*
- Boost follicle thickness by 18% in just 8 weeks (peptides + caffeine)*
- No drugs, no harsh chemicals — just a calmer, healthier scalp
Quote: “Every other shampoo just stripped my scalp raw. Regen actually calmed it down and within 2 months my hairline looked fuller. My close buddies even asked what I changed.”
Reduced Shedding & Stronger Roots
David L. Verified Customer
- Reduce daily shedding noticeably in 6 weeks*
- Improve hair shaft diameter, giving a denser look*
- Cleaner scalp sensation, lighter, less itchy by week 2*
Quote: “I was already using micro-infusion, but my crown was still struggling. Added Regen to prep my scalp before treatments—within 9 weeks the shedding dropped dramatically and my crown started filling in. Blown away!”
Complete Scalp Reset (With Halo)
Jake M. Verified Customer
- Combined Regen + Halo Scalp Massager = 3x better product distribution & circulation boost*
- Baby hairs along temples matured by 12 weeks*
- Flakes, itch, and greasy buildup gone
Quote: “The Halo turned my hair wash into an actual treatment. ~5 min of massage, and within 12 weeks my temple baby hairs matured into actual coverage. My scalp went from itchy and greasy to actually feeling normal again.”
Say Goodbye to Flakes, Itch, and Scalp Buildup — The Hidden Enemies of Hair Growth
Your scalp isn’t just skin — it’s the soil your hair grows from. When it’s inflamed, suffocated by buildup, or overrun with yeast, follicles can’t function. Most shampoos strip your scalp raw or pile on heavy silicones, making the problem worse.
Regen™ Shampoo & Conditioner was built differently. Powered by dermatologist-grade actives (Piroctone Olamine, Salicylic Acid, and Zinc PCA) plus peptide deposition technology, it resets your scalp environment in just 1–2 weeks:
- Eliminates flakes & yeast (dandruff drivers) → calmer, itch-free scalp
- Micro-exfoliates buildup → clears the way for growth treatments
- Balances oil production → no more heavy roots by midday
- Deposits copper peptides → supports tissue repair even after rinse
Healthy hair starts with a healthy scalp. Regen makes sure yours is finally ready to grow.
The Reset Starts With Your First Wash
Clinical research shows that the right actives can start transforming your scalp environment within days. With Regen™, users typically notice:
- In 1–3 washes: Less oil and buildup, scalp feels fresher and lighter
- In 1–2 weeks: Visible reduction in flakes and itch, calmer scalp tone
- In 4 weeks: Stronger, thicker-feeling strands thanks to peptide deposition (GHK-Cu + caffeine synergy)
- In 8 weeks: Optimized scalp foundation—clean, calm, and primed for growth treatments like micro-infusion or laser & red light therapy
Unlike traditional shampoos that strip or suffocate your scalp, Regen works below the surface of the cascade—reducing micro-inflammation, balancing sebum, and leaving active peptides behind even after rinsing. The result: a scalp that’s healthier, hair that feels stronger, and a foundation ready for visible growth.
Stop Scalp Sabotage From Day One
Clinical data shows that the PO-BHA-Zn triad can reduce flakes, calm irritation, and rebalance oil production within 1–2 weeks of consistent use—without sulfates, harsh detergents, or rebound dryness.
Most users notice their hair feels thicker, cleaner, and stronger—because Regen doesn’t just wash, it leaves behind copper peptides and caffeine to keep signaling even after rinsing.
No drugs. No dependency. Just a scalp environment finally primed for growth.
What Powers Regen™
The Dermatologist-Grade Stack
Ten actives, clinic-level doses, one sulfate-free formula.
Copper Tripeptide-1
The Micro-Environment Restorer
✓ Upregulates repair/angiogenesis programs; broad wound-healing gene modulation.
✓ Deposits via PQ-10/PQ-51 so a light peptide signal persists post-rinse.
Piroctone Olamine
The Anti-Flake Workhorse
✓ Targets Malassezia yeast (core driver of dandruff/SD) → fast itch/flake relief in 1–2 weeks.
✓ Reduces micro-inflammation that silently accelerates shedding.
Salicylic Acid
The Micro-Exfoliator
✓ Keratolytic/desmolytic: loosens compacted corneocytes & biofilm that block follicles.
✓ Improves penetration of leave-on actives and light therapy tolerance.
Zinc PCA
The Oil-Balance Controller
✓ Normalizes sebum without over-drying; antimicrobial/anti-inflammatory support.
✓ Zinc can inhibit 5-α-reductase in vitro (DHT-pathway support).
Copper Tripeptide-1
The Micro-Environment Restorer
✓ Upregulates repair/angiogenesis programs; broad wound-healing gene modulation.
✓ Deposits via PQ-10/PQ-51 so a light peptide signal persists post-rinse.
Salicylic Acid
The Micro-Exfoliator
✓ Keratolytic/desmolytic: loosens compacted corneocytes & biofilm that block follicles.
✓ Improves penetration of leave-on actives and light therapy tolerance.
Piroctone Olamine
The Anti-Flake Workhorse
✓ Targets Malassezia yeast (core driver of dandruff/SD) → fast itch/flake relief in 1–2 weeks.
✓ Reduces micro-inflammation that silently accelerates shedding.
Zinc PCA
The Oil-Balance Controller
✓ Normalizes sebum without over-drying; antimicrobial/anti-inflammatory support.
✓ Zinc can inhibit 5-α-reductase in vitro (DHT-pathway support).
The Only 2-in-1 Shampoo You’ll Ever Need
Most shampoos are just detergents with a sprinkle of biotin or “herbal extracts.” They clean the hair shaft but do nothing for the follicle environment where growth is decided. Regen™ is different. It delivers 10 clinically-backed actives in dermatologist-relevant concentrations inside a sulfate-free, silicone-free base — designed specifically for thinning scalps.
Beyond the hero ingredients you saw above, Regen includes supporting actives like Allantoin for irritation relief, Sodium Hyaluronate for hydration, Polyquaternium-10 for combability, and Biotin for keratin support. Every dose was chosen not for marketing, but because it amplifies comfort, follicle readiness, and consistency—so results keep you with us.
Traditional “hair growth” shampoos strip oil, irritate the scalp, or coat hair in silicones that suffocate roots. Anti-dandruff shampoos may calm flakes, but leave behind residues that block penetration. Regen™ gives you both: a PO-BHA-Zn dermatology-grade backbone to clear yeast, oil, and buildup plus peptide deposition technology that leaves behind follicle-priming signals after rinsing.
This isn’t just another shampoo that promises too much. Regen™ is the scalp reset technology that makes every other product in your routine work harder. Your follicles don’t need gimmicks — they need a foundation that clears, calms, and primes the growth environment. If your shampoo isn’t preparing your scalp, it’s working against you.
Make Other Treatments
Work Harder
Regen™ Shampoo & Conditioner is the “reset” that supercharges your routine.
When your scalp is congested (yeast, oil film, micro-scale) everything else fights uphill—serums sit on the surface, light therapy itches, massage feels tight. Regen fixes the terrain so your tools can actually do their jobs.
What “reset” really means
- Decongest – Piroctone Olamine tames Malassezia; Salicylic Acid lifts micro-scale; Zinc PCA normalizes oil.
- Rebalance – pH-smart and sulfate-free so the barrier stays calm.
- Prime – Caffeine and GHK-Cu deposit lightly after rinse, leaving a “ready” surface for treatment days.
- Comfort – Ectoine, Allantoin, Sodium Hyaluronate keep stamp/laser days comfortable.
How Regen™ Pairs With Your NovaMane System
+ Micro-Infusion System
- Clear scalp = max absorption: Regen removes oil, buildup, and flakes so micro-channels fill evenly with serum instead of letting actives slide off.
- Gentle comfort: pH-balanced actives like ectoine calm the scalp, so stamping feels smoother with less sting.
- Stronger carry-over: Regen leaves behind caffeine and copper-peptides that keep signaling repair between infusion sessions.
Get Best-In-Class Results
With NovaMane
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Regen™ 2-in-1 |
Nutrafol – Root Purifier |
Fleava – Copper Peptide |
Hims / Keeps – Thickening |
Nizoral / Drugstore Anti-Dandruff |
|---|---|---|---|---|---|
| See results in |
✅ 1–2 weeks: flake/itch ↓, lighter roots; 4–8 weeks: hair feels fuller |
⚠️ Gentle clean; slower change |
⚠️ Treatment-leaning; unclear |
⚠️ Cosmetic “thickening”; little terrain change |
✅ Flake relief fast; ⚠️ hair feel can collapse |
| Active with clinical backing |
✅ Piroctone 0.30% + BHA 0.30% + Zn PCA 0.30% |
⚠️ Microbiome comfort, no antifungal/BHA |
⚠️ Peptides, % undisclosed |
⚠️ Botanicals focus |
✅ Ketoconazole / PZ in select SKUs |
| Flake/yeast control (Malassezia) |
✅ Yes (PO 0.30%) |
✖️ No |
✖️ No |
✖️ No |
✅ Yes |
| Micro-exfoliation & oil balance |
✅ BHA 0.30% + Zn PCA 0.30% |
✖️ No BHA |
✖️ No BHA |
✖️ No BHA |
⚠️ Rare / varies |
| Post-rinse growth signaling |
✅ GHK-Cu 0.05% + PQ-51 deposition + Caffeine 0.6% |
✖️ No deposition; caffeine % unstated |
⚠️ Peptides, no deposition plan |
✖️ Brief contact only |
✖️ Medicated, no pro-repair signaling |
| Comfort & barrier |
✅ Ectoine + Licorice Salt + HA + Allantoin; pH 5.2–5.4 |
✅ Gentle |
⚠️ Varies |
⚠️ Basic; fragrance common |
⚠️ Menthol/SLS/SLES → sting/flatten |
| Sulfates / silicones |
✅ Sulfate-free / silicone-free |
✅ Sulfate-free |
⚠️ Varies |
⚠️ Often silicone “thickening” |
✖️ Many SLS/SLES; silicones |
| Designed to hand-off to treatments |
✅ Yes — primes for Micro-Infusion, plays clean with Lumen, boosts Halo massage |
⚠️ Gentle wash only |
⚠️ Treatment rinse, limited cleanse |
⚠️ Cosmetic / not treatment-prep |
✖️ Clarifies but not growth-prep design |
Reset Your Scalp
To Unlock Fuller-Looking Hair
Use Regen™ 3–5×/week (daily if very oily; every other day if sensitive) to clear yeast, lift buildup, and leave pro-repair signals that prep your scalp for growth.
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STEP 1
Cleanse & Prime
Work Regen into the scalp (not just hair) for 60–90 seconds.
- Piroctone targets Malassezia (flake/itch).
- BHA + Zn PCA loosen dead-cell film and balance oil.
- Use the Halo Scalp Massager for an even, stimulating scrub.
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STEP 2
Let Actives Work
Allow at least 60 seconds of contact time, then rinse.
- GHK-Cu + PQ-51 deposit light peptide signals post-rinse.
- Caffeine penetrates during wash time.
- Ectoine + HA + Allantoin keep the barrier calm and hydrated.
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STEP 3
Build the Routine (2–8 weeks)
- Week 1–2: Scalp feels calmer; flakes/itch reduce; roots feel lighter.
- Week 3–4: Hair looks fuller; scalp looks healthier.
- Week 6–8: Ideal base for Micro-Infusion days and Lumen sessions
Here’s What Men Love Most
About Regen™ 2-in-1 Scalp Reset
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It Clears the Real Root Causes—Not Just the Hair
Unlike “biotin shampoos,” Regen is built from the hair-loss cascade. The PO-BHA-Zn triad (Piroctone Olamine, Salicylic Acid, Zinc PCA) tackles yeast, adherent micro-scale, and excess oil—quieting the inflammation that blunts growth.
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Visible Relief in 1–2 Weeks
Most notice fewer flakes/itch and lighter roots within the first 1–2 weeks of consistent use (3–5×/week; daily if very oily). A calmer scalp = better handling and fuller-looking hair.
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Peptide Signals That Keep Working After You Rinse
GHK-Cu + caffeine are carried by smart conditioners (PQ-10/-51), leaving a light, pro-repair cue on scalp and hair—without heaviness or buildup.
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A True 2-in-1: Cleanse + Light Condition, Zero Collapse
Sulfate-free surfactant trio cleans deeply without stripping, while panthenol + hydrolyzed wheat protein add slip and body. No heavy silicones; color-safe for straight, curly, and coily hair.
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System-Ready (Great Solo, Perfect With NovaMane)
Regen primes the canvas for everything else—clean channels for Micro-Infusion, comfortable sessions for Lumen™, and better distribution with Halo™. Silicone-free and pH-smart so nothing scatters light or gums up the scalp.
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Drug-Free, Dermatologist-Level Doses
Clinical-grade actives, sulfate-/silicone-/paraben-free, pH 5.2–5.4, plus ectoine, licorice salt, HA, and allantoin for comfort. Patch-test advised for sensitive scalps; designed for men & women.
A Calmer, Fuller-Looking Scalp in 180 Days Or Your Money Back
Didn’t see the flake relief, lighter roots, or thicker-looking hair you expected? You’ve got 180 days to send it back for a full refund.
Frequently Asked Questions
You got questions. We got answers.
When will I start seeing results?
When will I start seeing results?
Most people feel a difference in the first 1–3 washes (lighter roots, cleaner feel). By 1–2 weeks: flakes/itch visibly calm down. By 3–4 weeks: hair handles easier and looks fuller at the roots. Keep it steady through 6–8 weeks to lock in a clean, balanced baseline.
How often should I use Regen?
How often should I use Regen?
Use 3–5×/week.
- Very oily / flake-prone: daily for 7–10 days, then 4–5×/week.
- Normal: 3–4×/week.
Sensitive: every other day (2–3×/week). Always massage 60–90s, then 60s dwell before rinsing.
Is it safe for color-treated or keratin-treated hair?
Is it safe for color-treated or keratin-treated hair?
Yes—sulfate-free and pH 5.2–5.4. Gentle on color and treatments. (As with any wash, avoid shampooing for 48h after fresh color.)
What ingredients are in the shampoo? (Full INCI & roles)
What ingredients are in the shampoo? (Full INCI & roles)
Hero Actives
- Piroctone Olamine - Targets Malassezia on the scalp; helps visibly reduce flaking and itch within 1–2 weeks so the whole system performs better
- Salicylic Acid (BHA) - Gently loosens compacted scale and buildup so oils, yeast, and residue lift during the wash; improves access for other actives
- Zinc PCA - Provides antimicrobial/anti-inflammatory support while PCA adds humectancy; helps keep roots fresh without over-drying
- Caffeine - Shown to counter androgen-related suppression in follicle models; penetrates via the follicular route during shampoo contact time
- Copper Tripeptide-1 (GHK-Cu) - Supports repair/angiogenic signaling and a healthier ECM; light deposition can persist post-rinse for a subtly fuller feel
- Ectoine - Stabilizes proteins and membranes; helps reduce sting/tightness on active-rich routines without adding weight
- Polyquaternium-51 - A biomimetic film former that boosts moisture feel and helps caffeine/GHK-Cu linger after rinse-off
- Dipotassium Glycyrrhizate - Licorice-derived salt that helps soothe the scalp and temper itch/irritation signals
- Panthenol + Hydrolyzed Wheat Protein - Panthenol improves elasticity and reduces breakage; wheat protein adds airy grip for fuller-looking hair right out of the shower
- Rosemary Leaf Extract + Green Tea Leaf Extract - A clean, decolorized rosemary plus trimmed green tea provide supportive antioxidant and scalp-comfort benefits
Complementary Co-Actives
- Biotin - supports the hair fiber’s keratin infrastructure; complements panthenol/protein for stronger-feeling strands.
- Allantoin - Classic anti-irritant that buffers the active load for comfortable daily use
- Sodium Hyaluronate - Surface hydration even in a rinse-off; offsets any BHA-related dryness
- Glycerin - Primary humectant in a sulfate-free chassis; supports soft, non-stripping foam
Vehicle & Cleansing System
- Sodium Lauroyl Methyl Isethionate - Rich, gentle lather with low irritation
- Sodium Lauroyl Sarcosinate - Deep but mild cleanse; boosts rinse-clean feel
- Cocamidopropyl Betaine - Amphoteric buffer that softens anionics for scalp comfort
Preservative & Stability System
- Phenoxyethanol + Ethylhexylglycerin - Clean, globally accepted broad-spectrum preservation
- Sodium Phytate - Chelator that helps control metal-catalyzed color/oxidation while being friendlier to copper complexes than EDTA
- pH 5.2–5.4 - Barrier-friendly; compatible with PO/BHA and cationic deposition
✅ Sulfate-free (no SLS/SLES)
✅ Silicone-free (fullness without root-flattening films)
✅ Balances oil, reduces visible flaking, and improves scalp comfort
✅ Pairs well with NovaMane’s Microinfusion system and Lumen laser cap
Will this replace my conditioner?
Will this replace my conditioner?
Often, yes. Regen provides light slip/body (panthenol + hydrolyzed proteins). Very long/coily/dry hair may still want a mid-lengths/ends conditioner—keep heavy creams off the scalp.
How does it actually work?
How does it actually work?
Regen is built from the scalp cascade, not the hair shaft:
- Decongest: clinical BHA + zinc PCA loosen film and rebalance oil; piroctone keeps yeast in check.
- Prime: caffeine + copper peptides lightly deposit post-rinse (via cationic polymers) to support a healthier environment.
Comfort:ectoine, licorice salt, HA, allantoin keep the barrier calm so you can stay consistent.
Will I “shed” more at first?
Will I “shed” more at first?
A temporary increase isn’t typical with Regen. You may see flaky sloughing in week 1–2 (that’s the micro-exfoliation working). If you notice unusual hair fall, reduce frequency and check in with your dermatologist.
Can I use Regen daily?
Can I use Regen daily?
Yes—especially if you’re very oily or exercise often. If you ever feel dry/tight, drop to every other day.
Can I leave it on longer for extra effect?
Can I leave it on longer for extra effect?
The sweet spot is 60–90s massage + 60s dwell. If you tolerate well, you can extend dwell to 2–3 minutes. Sensitive scalps should stick to the standard.
Does it contain sulfates, silicones, or parabens?
Does it contain sulfates, silicones, or parabens?
No. Sulfate-free, silicone-free, paraben-free. Drug-free and non-hormonal.
What does it smell like?
What does it smell like?
Unscented. Regen is fragrance-free—no perfume or masking scents. Most users notice no smell at all. Dye-free; a faint natural blue tint from copper peptides is normal.
Is it okay during pregnancy or breastfeeding?
Is it okay during pregnancy or breastfeeding?
Regen uses low-level, rinse-off BHA and non-drug actives. Many providers consider this acceptable, but we always recommend confirming with your healthcare professional first.
Can I use Regen with medicated dandruff shampoos (e.g., ketoconazole)?
Can I use Regen with medicated dandruff shampoos (e.g., ketoconazole)?
Yes. Use Regen as your primary wash and rotate the medicated shampoo 1–2×/week as needed (not in the same wash). If you’re under a doctor’s plan, follow their guidance.
How does Regen pair with other NovaMane products?
How does Regen pair with other NovaMane products?
Regen creates a clean, calm base so leave-ons and devices contact the scalp better.
- On treatment days (e.g., stamping): wash before or ≥8–12h after. If you’re sensitive, wait 24h post-stamp.
For light therapy: wash, dry scalp, then do your session.
I have seborrheic dermatitis—will this help?
I have seborrheic dermatitis—will this help?
Regen includes dermatology-favored actives that help reduce flaking/itch and balance oil, common SD complaints. It isn’t a drug; for persistent or severe cases, work with your dermatologist.
Who shouldn’t use Regen?
Who shouldn’t use Regen?
Anyone with a known salicylate/aspirin sensitivity, broken/compromised skin, or an active scalp infection. Patch test first if you’re sensitive.
How do I patch test?
How do I patch test?
Apply a small amount behind the ear/hairline, leave 5 minutes, rinse, and monitor 24h. If redness/burning/itch occurs, reduce frequency or discontinue.
Will it make my hair flat or greasy?
Will it make my hair flat or greasy?
No heavy silicones. The base is deep-but-gentle, and the conditioning is light—most users report clean lift at the roots.
How long will a bottle last?
How long will a bottle last?
100 mL lasts ~5 weeks at 3–5 uses/week (hair length + amount vary).
What makes Regen different from other shampoos?
What makes Regen different from other shampoos?
- Built from the hair-loss cascade (yeast • film • oil • micro-inflammation).
- Clinical actives at meaningful levels, not “label sprinkles.”
- Peptide deposition in a rinse-off (rare) to keep a light pro-repair signal after rinsing.
- Sulfate-free cleansing + pH-smart comfort = consistency without collapse.
What if I don’t notice a difference?
What if I don’t notice a difference?
Make sure you’re:
- Massaging 60–90s and giving 60s dwell.
- Using 3–5×/week (daily initially if very oily).
- Keeping heavy conditioners/oils off the scalp.
Still not feeling it after 6–8 weeks? You’re covered by our guarantee—reach out and we’ll take care of you.
Customer Reviews
Minoxidil gave me chest pains. Finasteride killed my sex drive. This actually worked, and I feel better than before I started losing hair
Testosterone therapy was destroying my hair. This was the only thing that stopped the shedding without interfering with my hormone optimization.
I use Regen before applying my minoxidil and it makes absorption better.
I'd been on finasteride for 2 years with minimal results. Within 2 weeks of addressing the inflammation, I saw more regrowth than in the previous 24 months combined.
Been using novamane regen for about a month now and honestly my scalp feels cleaner than ever.. the itching's gone and my hair seems thicker around the crown.
Would give it 5 stars if it wasn’t out of stock half the time! Clearly everyone’s buying it.
Was recommended by a friend and now I’m hooked. Just reordered my second bottle.
I started using Regen alongside my hair growth routine and it made a massive difference. My scalp used to get clogged up with product and oil, but this cleared it all out. It’s not harsh or drying either — just super balanced. Honestly feels like a facial for your scalp.
Had mild itchiness before, gone in a week. Hair also smells great.
I’ve been dealing with seborrheic dermatitis and honestly, this was the first product that calmed it down without making my scalp tight. The zinc and peptides combo works wonders. My skin doesn’t feel inflamed anymore and I can finally wear darker shirts again.